Development on the pulse of time
Vaccines help to make the body immune to a disease by introducing an attenuated form of the pathogen, an inactivated form or a purified form of the pathogen. This allows the immune system to develop an immune response without the person having to go through the disease themselves. Once the immune system has recognized the pathogen, it can build up a protective immune response that protects the person from future infections.
The production process comprises a series of steps such as propagation in bioreactors, mechanical disruption of the cells, separation by centrifugation, filtration and ultrafiltration, purification, protein selection, combination of different virus strains and filling into vials, ampoules or syringes.
The mechanical disruption of the cells is achieved with agitator bead mills from WAB-GROUP. This process step makes it possible to open the cells without damaging the ingredients. Gentle disruption is what makes the subsequent process steps possible in the first place. WAB-GROUP has been providing the necessary process technologies for this key step in vaccine production for over 50 years.
The requirements for this process have increased significantly in recent years. In the 1990s, cleaning of parts in contact with the product was carried out by means of chemical sterilization; today, the mills are designed aseptically and sterilization is carried out fully automatically on site using steam. These measures improve process quality and safety in the production of vaccines.
The associated challenges were mastered by the engineers of the WAB-GROUP, and in cooperation with our customers new concepts for production were developed and implemented.
Are you interested in the production of vaccines and would like to learn more about our solution on this topic? Then contact us via the contact form and talk to one of our process experts worldwide.

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